InterContinental Lyon - Hotel Dieu is set within the restored Grand Hotel-Dieu, one of Lyon’s landmark historic buildings on the banks of the Rhône. The hotel combines 18th-century architecture, courtyards and vaulted public spaces with contemporary rooms and suites by designer Jean-Philippe Nuel. Dining at Epona, the dramatic Le Dôme bar and spa facilities add to its sense of occasion. Its location places guests between the Presqu’île, the river and the city’s culinary heritage, making the building itself a central part of the stay.