Just off Via del Tritone, Palazzo Talìa occupies a 16th-century Roman building once associated with the Collegio Nazareno. Historic frescoes, marble, timber panelling and handcrafted tiles are set against contemporary furniture and theatrical colour, creating rooms and suites with distinct identities rather than a uniform scheme. Tramae restaurant extends into a planted courtyard, while Bar della Musa uses mirrored surfaces and glowing amber tones beneath the old walls. A compact spa and indoor pool lie below ground, leaving the central courtyard and layered architectural details to connect the hotel with its Renaissance origins.